Endocrine Abstracts

In addition to cellular interactions via cytokines, the immune and skeletal systems share various molecules, including transcription factors, signaling molecules and membrane receptors1. RANKL stimulates osteoclastogenesis through NFATc1 in cooperation with immunoglobulin-like receptors, using the immunomodulatory molecules for signalling2. Here I will discuss emerging topics in osteoimmunology including the mechanisms underlying bone cell communication: ...